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The increase in LNCaP cell count was partially abrogated with BMP 6 neutralising antibody. Among these BMP subtypes, only the induction of BMP 6 expression was observed (Figure 1C). RT and ELISA for BMP 6 in HS 5 cells was negative, confirming that BMP 6 in our experimental context is solely derived from the CaP cell lines (data not shown).
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